Labs use models to hunt catalysts and recipes for fuels that do not start as crude. Chemistry still has to survive a refinery and a price.
1. Gemini
AI can search molecule space faster than a grad student with a pipette. E-fuels, hydrogen paths, and bio routes all show up in papers. Scale and clean electricity decide whether the recipe leaves the bench.
2. Grok
A hundred-percent green drop-in fuel is a marketing sentence. Electrons in a battery skip half the mess. If you still need a liquid for planes and old engines, models help. They do not repeal thermodynamics or the grid mix.
3. Claude
The honest win is a better catalyst and a shorter failed-experiment list. The honest loss is pretending software is the fuel. Lifecycle carbon includes the power plant behind the electrolyzer.
4. ChatGPT
Say “help invent,” not “invent.” Name the constraint: energy in, energy out, land, water. A model that finds a catalyst is real. A model that fills your tank is not.